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Product Name
14-3-3 sigma Rabbit mAb
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Gene ID
2810
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SwissProt ID
P31947
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Gene Name
SFN
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Alternative Names
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
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Background
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
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Research Field
Neuroscience
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 28 kDa; Observed MW: 28 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-5C8
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human 14-3-3 sigma
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.