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Product Name
Phospho-AKT (Ser473) Rabbit pAb
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Background
Swiss-Prot Acc.P31749.An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.
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Alternative Names
AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha;
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Immunogen
A synthesized peptide derived from human Phospho-Akt(Ser473)
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/100-1/500
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Molecular Weight
60kDa
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Antibody Type
Primary Antibody
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Clonality
Polyclonal Antibody
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Gene Name
AKT1
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Conjugation
Unconjugated
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Isotype
Rabbit IgG
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Host
Rabbit
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Application
WB,IHC-P,ICC/IF
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Purification
Affinity Chromatography
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Reactivity
Human,Mouse,Rat
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
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SwissProt ID
P31749
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Research Field
Signal Transduction
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Gene ID
207
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Modification
Phosphorylated